Mus musculus Gene: C5ar1
Summary
InnateDB Gene IDBG-65814.1
Last Modified 2018-06-05 [Report errors or provide feedback]
Gene Symbol C5ar1
Gene Name C5a anaphylatoxin chemotactic receptor 1
Synonyms C5aR; C5r1; Cd88; D7Msu1;
Species Mus musculus
Ensembl Gene ENSMUSG00000049130
Encoded Proteins
C5a anaphylatoxin chemotactic receptor 1
C5a anaphylatoxin chemotactic receptor 1
C5a anaphylatoxin chemotactic receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:16246743-16259540
Strand Reverse strand
Band A2
Transcripts
ENSMUST00000050770 ENSMUSP00000060003
ENSMUST00000168818 ENSMUSP00000129972
ENSMUST00000209442 ENSMUSP00000148140
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004875 complement receptor activity
GO:0004878 complement component C5a receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0002430 complement receptor mediated signaling pathway
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0010575 positive regulation of vascular endothelial growth factor production
GO:0010759 positive regulation of macrophage chemotaxis
GO:0030593 neutrophil chemotaxis
GO:0032494 response to peptidoglycan
GO:0038178 complement component C5a signaling pathway
GO:0042789 mRNA transcription from RNA polymerase II promoter
GO:0045766 positive regulation of angiogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0050830 defense response to Gram-positive bacterium
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0090023 positive regulation of neutrophil chemotaxis
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0031410 cytoplasmic vesicle
GO:0045177 apical part of cell
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Neutrophil degranulation pathway
Signaling by GPCR pathway
Innate Immune System pathway
Class A/1 (Rhodopsin-like receptors) pathway
Complement cascade pathway
GPCR ligand binding pathway
Immune System pathway
Peptide ligand-binding receptors pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
Regulation of Complement cascade pathway
GPCR downstream signalling pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Complement and coagulation cascades pathway
Staphylococcus aureus infection pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001173550 NM_007577
OMIM
CCDS CCDS20846
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas