Mus musculus Gene: Cd80
Summary
InnateDB Gene IDBG-72472.1
Last Modified 2018-06-05 [Report errors or provide feedback]
Gene Symbol Cd80
Gene Name T-lymphocyte activation antigen CD80
Synonyms B71; Cd28l; Ly-53; Ly53; MIC17; TSA1;
Species Mus musculus
Ensembl Gene ENSMUSG00000075122
Encoded Proteins
T-lymphocyte activation antigen CD80
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:38458933-38486933
Strand Forward strand
Band B4
Transcripts
ENSMUST00000099816 ENSMUSP00000097404
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 2 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015026 coreceptor activity
Biological Process
GO:0007165 signal transduction
GO:0031295 T cell costimulation
GO:0042102 positive regulation of T cell proliferation
GO:0046641 positive regulation of alpha-beta T cell proliferation
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0071222 cellular response to lipopolysaccharide
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0098636 protein complex involved in cell adhesion
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
CD28 co-stimulation pathway
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling pathway
PIP3 activates AKT signaling pathway
Intracellular signaling by second messengers pathway
CD28 dependent PI3K/Akt signaling pathway
Costimulation by the CD28 family pathway
CTLA4 inhibitory signaling pathway
Immune System pathway
Signal Transduction pathway
Adaptive Immune System pathway
Negative regulation of the PI3K/AKT network pathway
CD28 dependent Vav1 pathway pathway
KEGG
Cell adhesion molecules (CAMs) pathway
Toll-like receptor signaling pathway pathway
Intestinal immune network for IgA production pathway
Type I diabetes mellitus pathway
Autoimmune thyroid disease pathway
Systemic lupus erythematosus pathway
Rheumatoid arthritis pathway
Allograft rejection pathway
Graft-versus-host disease pathway
Viral myocarditis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q00609
TrEMBL Q549R2
UniProt Splice Variant
Entrez Gene 12519
UniGene
RefSeq NM_009855 XM_006521737 XM_017316857 XM_017316858
OMIM
CCDS CCDS28168
HPRD
IMGT
MGI ID MGI:101775
MGI Symbol Cd80
EMBL AF065894 AF065895 AF065896 AJ278965 AY278186 BC131959 D16220 L12585 L12586 L12587 L12588 L12589 X60958
GenPept AAA37240 AAD25877 AAD25878 AAD25879 AAI31960 AAP57303 BAA03748 CAA43291 CAC34306
RNA Seq Atlas 12519