Interaction: E2F1 :: MYC XML
Summary
InnateDB Group ID 462151
Short name E2F1 :: MYC
Full name E2F1 interacts with MYC
Interaction type physical association
Participants
Participant 1
Molecule: IDBG-67214
Molecule type: protein
Species: Homo sapiens
HUGO: E2F1
Full name: E2F transcription factor 1
Direction: input
Biological role: unspecified role
Participant 2
Molecule: IDBG-35442
Molecule type: dna
Species: Homo sapiens
HUGO: MYC
Full name: v-myc myelocytomatosis viral oncogene homolog (avian)
Direction: input
Biological role: unspecified role
Evidence Reference 1
InnateDB ID IDB-1730779.1
Last Modified 2014-11-29
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIND
Source database ID 153585
PMID 7892279
Interaction detection method electrophoretic mobility shift assay
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) E2F1 unspecified role NP_005216
2) MYC unspecified role AY214166
Evidence Reference 2
InnateDB ID IDB-1733571.1
Last Modified 2014-11-29
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIND
Source database ID 193064
PMID 11799067
Interaction detection method cross-linking study
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) E2F1 bait NP_005216
2) MYC prey NC_000008
Evidence Reference 3
InnateDB ID IDB-1736163.1
Last Modified 2014-11-29
Review status Unreviewed by InnateDB [Report errors or provide feedback]
Source database BIND
Source database ID 214977
PMID 12629508
Interaction detection method cross-linking study
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment
Participants
Participant Identification Method Experimental Role Participant Accession
1) E2F1 bait NP_005216
2) MYC prey NM_002467
Evidence Reference 4
InnateDB ID IDB-2063502.1
Last Modified 2017-05-28
Review status reviewed [Report errors or provide feedback]
Source database INNATEDB ALLERGY
Source database ID AAP-2063502
PMID 7892279
Interaction detection method electrophoretic mobility shift assay
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment Figure 2. A 32P-labelled oligonucleotide containing the -82 to -40 sequence of the human MYC P2 promoter was incubated with in vitro translated E2F1.
Participants
Participant Identification Method Experimental Role Participant Accession
1) E2F1 predetermined participant prey
2) MYC autoradiography bait
Evidence Reference 5
InnateDB ID IDB-2063505.1
Last Modified 2017-05-28
Review status reviewed [Report errors or provide feedback]
Source database INNATEDB ALLERGY
Source database ID AAP-2063505
PMID 7892279
Interaction detection method electrophoretic mobility shift assay
Host system invitro
Host organism
Cell status
Cell line
Cell type
Tissue type
Comment Figure 2. A 32P-labelled oligonucleotide containing the -82 to -40 sequence of the human MYC P2 promoter was incubated with in vitro translated E2F1 with and without TFDP1.
Participants
Participant Identification Method Experimental Role Participant Accession
1) E2F1 predetermined participant prey
2) MYC autoradiography bait