Help: Advanced Search for Genes and Proteins

This page provides the user with a number of options to search for genes or proteins of interest.

Choose organism - the AAP contains human, mouse and bovine genes and proteins.

The default on this page is to search for proteins/genes by the protein/gene name. A search of the AAP by the Protein/Gene name will automatically search the full gene name, all encoded protein names, the gene symbol and all synonym symbols (alternative names) for the gene. This option provides users the flexibility to find a gene/protein without having to know the HUGO name for it, which may be different from the common name(s). An exact search will be much faster and will return database entries that exactly match your query.

Several other options for searching the database are provided on this page:

  • InnateDB/AAP molecule ID: stable identifiers for a gene/protein in the AAP (e.g. IDBG-82738 is the ID for human TLR4).
  • HUGO gene symbol/ID: Human Genome Organization Gene Nomenclature Committee official symbol or numerical ID. (For human genes only).
  • Gene Ontology (GO) Accession: search for genes/proteins that are annotated by the GO consortium as being involved in a particular function, role or localization using the GO ID number (e.g. GO:0006954 is the ID for inflammatory response).
  • Gene Ontology (GO) Term: as above but allows free-text search (e.g. inflammatory). Using exact searches is not recommended here.
  • Ensembl ID: search using a human, mouse or bovine gene, protein or transcript accession number from the Ensembl database.
  • UniProt Accession: search using an accession number from the UniProt protein database.
  • Entrez Gene ID: search using an ID number from NCBI's Entrez Gene database.
  • RefSeq Accession: search using an accession number from NCBI's RefSeq database.
  • UniGene ID: search using an ID number from NCBI's UniGene database.
  • OMIM ID: search using an ID number from the Online Mendelian Inheritance in Man database.
  • EMBL Accession: search for a particular gene/protein based on the EMBL accession number.
  • PFAM Accession: search for encoded proteins containing matching PFAM domains.
  • InterPro Accession: search for encoded proteins containing matching InterPro domains.

Choose to return Genes (default) or proteins using the "Return a list of" menu.